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The effect of baicalin-Mg on ulcerative colitis was explored in a mouse model

Jorn Schneider H, Klotsche J, Saller B et al (2008) Associations of age-dependent IGF-I SDS with cardiovascular diseases and risk conditions: cross-sectional study in 6773 primary care patients

Clinical usefulness of proteomics in inflammatory bowel disease: a comprehensive review

During strong autoimmune responses or central nervous system infections, immune cells like leukocytes, monocytes, and macrophages can cross the BBB using paracellular and transcellular routes[187]

Increased reactive oxygen species (ROS) Dysfunctional mitochondria produce excessive ROS, which can damage mitochondrial DNA, proteins, and lipids, exacerbating mitochondrial impairment and triggering pro-inflammatory signaling (Vicente-Gutierrez et al., 2019