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The most frequent cause of bacterial transmission in healthcare institutions is the spread of microorganisms by the hands of healthcare workers

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77 In patients with COPD, several CC-chemokines like CCL-2, CCL-3 are upregulated to attract specific inflammatory cells, like macrophages, neutrophils and CD8(+) T-lymphocytes into the airway, suggesting the contribution of their respective receptor in the pathogenesis of the disease

Collectively, these data support the notion that increased GSH synthesis via NF-B-mediated EAAT3 upregulation serves to counteract the high levels of ROS in smokers