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Hence, administration of the GSH synthesis inhibitor L-buthionine-(S, R)-sulfoximine (BSO) alone and in co-treatment with the dopamine reuptake inhibitor 1-[2-[Bis-4(fluorophenyl)methoxy]ethyl]-4-3-(3-phenylpropyl) (GBR 12909) to rodents in neonatal period produces good neurodevelopmental models offering an opportunity to examine various neuroanatomical changes and different symptoms in schizophrenia spectrum

Current Genomics

doi: 10.1016/j.jconrel.2021.05.005

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In psychiatric settings, high-dose glycine (e.g., 0.8 g/kg per day) has shown promise as an adjunct in treating schizophrenia