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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Drinkwater N., Gee C.L., Puri M., Criscione K.R., McLeish M.J., Grunewald G.L., Martin J.L

A study done in mice found that only the chemical variant of cyclophosphamide that releases both acrolein and an alkylating metabolite phosphoramide mustard, but not the one that releases only acrolein, had increased the survival time of mice injected with leukaemia cells [85], supporting only weak cytostatic effects of acrolein

In this research results showed that TO and T6 had higher tumerone levels than those obtained through HD in the studies by Chowdhury et al

For clinicians : Intervening at the systems level targeting oxidative stress, toxin burden, microbiome imbalance, and metabolic dysregulation can meaningfully slow disease progression

Immune-mediated processes implicated in chemotherapy-induced peripheral neuropathy