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Keywords: Peyronies disease, Duplex Doppler ultrasound, Tunical plication, Plaque incision and grafting, Intralesional therapy, Oral Peyronies disease therapy, Dupuytrens disease, Ledderhose disease, Genetics INTRODUCTION Peyronies Disease (PD) is a superficial fibrosing condition of the penis characterized by the presence of fibrotic plaques often leading to penile deformity, with or without concomitant pain

These cells, while impervious to apoptosis-inducing therapies, remain vulnerable to lipid peroxidation, making ferroptosis a critical backdoor mechanism for eliminating residual, relapse-initiating cells (Lei et al., 2022)

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