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Upon examination and reviewing laboratory results showing elevated inflammatory markers, the physician diagnosed Reiters disease affecting the left hip

Disclosure of interest: JWG, PB, OJ, ZW, DC, GH are employees of Brainomix Limited Table 1

Patients Main Concerns Persistent inflammatory acne dealing with painful, recurring pustules Enlarged pores & irregularities visible stretching of pores around the central face Disappointed by previous laser treatments felt Fraxel didnt address the root cause Post-laser dryness concerns wanted to avoid extreme dryness caused by heat energy Desire for root-cause treatment needed something to suppress acne bacteria and restore skin health I keep breaking out with inflammatory acne, and my pores are becoming a major insecurity

In contrast, p28 increased the level of the TA and N isoforms of p63 in p53 wild type, but not in p53 mutated melanoma cells, while decreasing TA p73 in p53 wild type and mutated human melanoma cells