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Description

J Cell Biol 216(4):11631181

A wide range of phenyl and cycloalkyl substituents were employed with an ortho -aminoanilide moiety as the ZBG instead of the hydroxamic acid group, a structural modification that led to the masking of the HDAC6 inhibitory activity

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Siramesine, a lysosomotropic agent, and lapatinib, a dual tyrosine kinase inhibitor (TKI), can synergistically increase the level of ROS and accumulation of lipid peroxide in GBM, both of which are indicators of ferroptosis

This article is all about your superstar antioxidants and why they should be taken together to maximize their roles in protecting cells and supporting organ systems