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Therapeutically, small trials in humans are underway: one randomized trial in mild AD is testing an oral broad-spectrum antibiotic followed by FMT to reset the microbiome [142]

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Inheritable genetic mutations that release excessive TGF- from the ECM or induce over-production of the ligand will be specifically discussed in section Genetic mutations in TGF- signaling components cause bone-associated disorders

It was subsequently discovered that these symptoms occurred while the participant was using control eye drops