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In the past, PTNBs were usually kept on a strict diet and received calorie intakes quite below their energy requirements for a prolonged time, during some days or weeks, for fear of presenting metabolic complications derived of an early enteral nutrition or a rapid increase in macronutrients

10.1016/j.biopha.2020.110379 34 GaoY.ChuS

According to the International Diabetes Federation (IDF) (2019), 9.3% of adults around the world, amount to 463 million people, have T2DM (1)

Injury to the bile duct occurs rarely at a rate of 0.3 to 0.5 percent yet it leads to serious persistent complications that require strictures and cholangitis treatment as well as reconstructive surgical operations[27]

Clinical working case definition, diagnostic and treatment protocols