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Community sources report fewer minor illnesses (colds, sinus infections) beginning in this window, though this is difficult to attribute specifically to glutathione versus seasonal variation

YiWClarkPMMasonDEKeenanMCHillCGoddardWAet al

Notably, all model animals based on a HFD are associated with obesity and IR

Masadah R, Ikram D, Rauf S

The basic idea is that fecal matter builds up in the colon and leads to autointoxication, which is "an ancient theory based on the belief that intestinal waste products can poison the body and are a major contributor to many, if not all, diseases," according to a report in the Journal of Clinical Gastroenterology