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doi: 10.3233/JAD-130831

In the era when the initial impressions frequently depend on the healthy, radiant look of a person, there is an increased demand for efficient skincare treatment

Taking into account the mechanism of protein interaction with the immobilized ions, careful should be taken in IMAC to avoid strong reducing and chelating agents in any of the buffers (as for instance, EDTA), as they will reduce or strip the immobilized metal ions (Carson et al., 2003