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Investigating silibinin anti-cancer effects through drug delivery system The low water solubility and poor bioavailability of silibinin limit its therapeutic efficacy at tumor sites

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Furthermore, infertile individuals with aberrant DNA methylation-imprinting were reported to have marked oligoasthenoteratozoospermia and oligozoospermia (120)

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Noh, K.-M

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In addition, since cell death processes may intricately regulate each other, the straightforward inhibition of a particular cell death modality may not present the optimal therapeutic solution against the complexity of diseases pathophysiology

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TNF- acts through several mechanisms, directly affecting neuronal function, reducing 5-HT synthesis, impairing gut barrier integrity, and promoting intestinal muscularis inflammation

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