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PD patients commonly show cognitive deficiencies when glutamate levels rise above normal levels ( Furthermore, Rg1 has been confirmed to raise BDNF levels, while triggering TrkB receptor activation to initiate PI3K/Akt and MAPK/ERK signal transmission

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doi: 10.1038/s41420-020-00356-1 35 LesjakMSiminNSraiSKS