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Mittl et al

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Several synthetic AMPs based on L-amino acid substitutions, such as iseganan (protegrin analogue), omiganan (indolicidin analogue), and P113 (histatin analogue), have progressed to late-stage clinical trials

Additionally, an Indian expert panel emphasized that apremilast is not contraindicated in patients with liver disease and can be safely administered without dose adjustments in patients with hepatic impairment (Rajagopalan et al

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