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Kennedy.) They may be longer-lasting than natural versions, or raise concentrations beyond what would naturally occur in the body

Restricted cystine uptake by tumor cells reduces T-cell ferroptosis and restores anti-tumor immunity To explore the impact of impeding tumor competition for cystine on T cell anti-tumor immunity, we generated Slc7a11 knockdown (KD) B16F10 cells (Fig

Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1 gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway

Nat Cell Biol 24:13061318