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Preclinical studies have examined the peptide in models of gastrointestinal injury, epithelial disruption, and anastomosis healing where researchers analyze mucosal architecture, vascular integrity, and epithelial continuity following tissue damage [1]

In this sense, it has been reported that miR-132 is negatively regulated by hypoxia, which increases MMP-9 activity, which degrades TJ proteins in brain endothelial cells or extracellular matrix components in the NVU, favoring an increased permeability of the BBB (Cichon et al., 2017)

A peptide is a small chain of amino acids, which are the building blocks of proteins in the body

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HPLC purity verification and mass spectrometry confirmation are performed for every lot