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That research suggested that the nondigestible -(16)-branched (14)--D-glucan found in high molecular weight fraction might be responsible for its anti-inflammatory properties by interacting with TLR2 receptors rather than Dectin-1 or CR3 receptors

Importantly, crucial fatigue, exercise intolerance and myalgia are not specific of ME/CFS, but are shared by patients suffering from primary mitochondrial diseases with mutations in either nuclear or mitochondrial DNA (188)