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Homayoon, N

Based on these naturally occurring phenomena, GR of malaria parasites and their host cells represent attractive antimalarial drug targets

285 In addition, SRC kinases activated by ROS mediate ERK activation via Raf or EGFR signaling

First, parkin can directly recycle oxidized glutathione (GSSG) under rising ROS conditions, generating one reduced GSH molecule, which in turn results in the S- glutathionylation of parkin itself (P-SH + GSSG $\to$ P- S- SG + GSH) (Figs