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Trichothecenes are considered extremely toxic and have been used as biological warfare agents

This week, a patient came into my practice after being in a minor car accident

In this review, we summarise the present understanding of cNF pathogenesis including recent studies that propose a putative tumour cell of origin, the identification of mutations in NF1 and other genes in cNF, the role of the tumour microenvironment and endocrine signalling in cNF, and past, recent and ongoing clinical trials for cNF

Proc Natl Acad Sci United States America (2014) 111(39):1421722

ROS oxidizes cysteine residues on actin and actin-regulatory proteins, altering their function and promoting actin filament disassembly or abnormal polymerization 28