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Intriguingly, at the end of the in vivo experiment, lipid peroxidation levels, as determined by 4-HNE staining, were still significantly increased after combined LDHB silencing and RSL3 treatment (Supplementary Fig

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The researchers also noted an increased sociability index, with no changes in anxiety behavior

However, spontaneous decomposition of these NO donors emphasizes the need for a delivery scaffold that prolongs the decomposition process and enables controlled release

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