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Stevenson TJ, Johnson RH, Savistchenko J, Rustenhoven J, Woolf Z, Smyth LCD, et al

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

4M + S4F), indicating AST reduction is indeed caused by clearance of senescent cells

FIGURE 2 3.3 Hypoxic-glucose deprivation conditions can induce senescence in endothelial cells Unlike the previously mentioned natural aging models and progeria models, there is another common but often overlooked endothelial cell aging model: hypoxia-induced endothelial cell senescence