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You may feel unsteady in the dark, on uneven ground, or when stepping off a curb

doi:10.1016/S0531-5131(03)00757-X

This type of respiratory depression has the greatest risk associated with the beginning of therapy and/or an increase in the amount of tramadol prescribed (61)

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A 13-amino acid linear peptide analog of alpha-melanocyte-stimulating hormone that selectively activates MC1R to stimulate eumelanin synthesis and photoprotective pathways in clinical research