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Furthermore, BCAAs promote macrophage polarization towards the pro-inflammatory M1 phenotype through the INFGR1/JAK1/STAT1 signaling pathway, thereby enhancing inflammatory responses and insulin resistance (105)

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Metabolism and Bioavailability of Glucosinolates Metabolism The hydrolysis of glucosinolates, which is catalyzed by a class of enzymes called myrosinases (-thioglucosidases), leads to the formation of breakdown compounds, such as thiocyanates, isothiocyanates, indoles, oxazolidine-2-thiones (e.g., goitrin), epithionitrile, and nitrile ( Figure 2 )

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