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doi:10.1016/s0952-3278(97)90587-1 Liu D, Pei D, Hu H, Gu G, Cui W

Serious side effects are extremely uncommon, but allergic reactionsincluding rash, swelling, or breathing difficultiesshould be treated as medical emergencies

or have systemic infections should not undergo the VenaSeal procedure

It's a vascularized connective tissue matrix with lymphatic drainage that governs peptide absorption kinetics in ways muscle tissue cannot replicate