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Levels of released AMC were measured using an excitation wavelength of 380 nm and an emission wavelength of 460 nm with an automatic multi-well plate reader

Starting with a lower dose and titrating up can frequently mitigate this

Understanding the molecular and cellular mechanisms underlying the loss or gain of disorder-related detrimental effects mediated by astrocytes in different contexts has the potential to identify new treatment strategies for a wide variety of CNS disorders

ABCD1 deficiency can induce the spontaneous production of ROS in low doses or even in the absence of VLCFA

Zung A, Phillip M, Chalew SA, Palese T, Kowarski AA, Zadik Z