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Laboratory studies examining this interaction have documented that the compound can stimulate lipolytic activity in adipocyte models through 3-AR-dependent pathways

This effect was secondary to an increase in the levels of plasma insulin and reduced insulin sensitivity [3]

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Maladie dAlzheimer : sur un modle de maladie dAlzheimer chez le rat, recevant 70 140 mg/kg/jour de silymarine pendant 1 mois, on constate une amlioration des fonctions cognitives, une rgression des plaques amylodes au niveau du cerveau et une suppression de lexpression du prcurseur protique de lamylode (APP), confirmant leffet anti-amylodogne de la silybine observ in vitro