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This is the bidirectional communication system between the gastrointestinal tract and the central nervous system

Approximately 40-50% of people are deficient in B12, with rates reaching 50% among those with hypothyroidism

Diagnosis of Vitamin B12 Deficiency The diagnosis of vitamin B 12 deficiency has traditionally been based on low serum vitamin B 12 levels, usually less than 200 pg per mL (150 pmol per L), along with clinical evidence of disease

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Hence, Smartamine is resistant to the rumen pH, but is soluble in lower pHs, such as the post-ruminal environment, being undegradable in the rumen and immediately released in the abomasum