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Acute tubular necrosis (ATN) scores were attenuated in the Luseo group compared to those in the vehicle group (Fig

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doi: 10.1002/tox.22920 81 HuangfuD.MaehrR.GuoW.EijkelenboomA.SnitowM.ChenA

4.3.5 Altered drug mechanism of action Repurposed drugs may exert their effect on the CNS tumor differently from their actions in the originally FDA-approved tumor type (108, 109)

The theory suggests these peptides may influence gene expression through epigenetic mechanisms, though the precise molecular interactions remain an area of ongoing investigation