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A Possible Antidote for Tylenol (Paracetamol) Overdose ACSH Acetaminophen metabolism. Acetaminophen is metabolized primarily by sulfation and glucuronidation. However, it can also be oxidized by CYPs to form NAPQI. NAPQI can then interact with cellular macromolecules, resulting in toxicity, or it can be detoxified Acetaminophen MSK Medbullets Step 1 Acetaminophen Anesthesia Key PGC 1 Induces Susceptibility To Acetaminophen Driven Acute Liver Failure Scientific Reports
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