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During this treatment, GSH-CDs also effectively inhibited the expression of SASP in NPCs and promoted the anabolic process

Barres BA (2008)

Recent CU can effectively alleviate liver cirrhosis (Zhang et al., 2024), alter the fecal microbiota composition in rats afflicted with liver fibrosis, reduce the abundance of Bacteroidetes, increase the abundance of Firmicutes and Proteobacteria, and inhibit the activity of TLR4/NF- signaling pathway, leading to reduced expression of inflammatory factors (IL-6, TNF-, IL-8) (Zheng et al., 2022)

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These findings indicate that CPX-351 is a valuable treatment option, especially when subsequent allo-SCT is considered