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Mutat Res 1998

Dihexa acts primarily through hepatocyte growth factor (HGF) signaling by potentiating HGF/c-Met receptor interaction

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The most potent inhibitor of TGR, however, was a gold-containing complex called auranofin, low levels of which inhibited TGR in test tubes, completely killed larval, juvenile, and adult parasites living in laboratory dishes within hours, and more than halved the worm burden in infected mice

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