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This can occur due to a genetic predisposition (vitamin B12 deficiency anemia is more prevalent in people with a northern European heritage or with a family history of this condition)

Findings revealed persistent metabolic consequences of maternal hyperglycemia on long-term offspring glucose homeostasis, notably extending to glycemic levels below current GDM diagnostic thresholds

Several studies have demonstrated that in vitro heat stress has detrimental effects on various aspects of cytoplasmic and nuclear oocyte maturation 70 , including cytoskeletal rearrangement 14 , meiotic spindle formation 14,67 and early embryonic mitotic failure 71

1, Table 1 and Methods

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