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*The American Journal of Clinical Nutrition*, 87(3), 688-691

Gwenalle Douaud, Helga Refsum, Celeste A

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Propionate, itself a substrate for intestinal gluconeogenesis, activates its expression via a gut-brain neural circuit involving the fatty acid receptor FFAR3 (245)

Nausea (reported by up to 44% on higher doses ), bloating , burping , and constipation all contribute to increased reflux risk through different mechanisms