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10.1016/j.jphs.2021.08.011 25 OkuboH.AndoH.NakaderaE.IkejimaK.ShiinaS.NagaharaA

This phenomenon facilitates immune evasiveness, thereby facilitating the survival of tumor cells during chemotherapy

Sterol regulatory element-binding protein 1c (SREBP-1c) is a key transcription factor governing fatty acid and triglyceride synthesis, and its activity is markedly enhanced under conditions of high glucose and hyperinsulinemia (29, 30)