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Even at doses 200-fold above the effective GH-releasing dose, ipamorelin did not stimulate cortisol demonstrating a true selectivity threshold rather than merely a dose-separation effect

In a study by Cohen et al[41] probability of avoiding colectomy at long-term follow-up (5.5 years) was 66% in patients receiving cyclosporin and azathioprine/mercaptopurine compared with 40% in those who received cyclosporin alone