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Bessis D et al describieron un cuadro de urticaria pigmentaria en una mujer de 31 aos sin antecedentes patolgicos relevantes e interacciones farmacolgicas, que presentaba unas mculas rojo-amarronadas con un prurito moderado, dispersas en los laterales de los muslos y piernas y estaban confinadas a los lugares de las inyecciones, de 18 meses de duracin (15)

Additional studies are needed to identify other potential contributing factors

Single-cell RNA sequencing revealed widespread downregulation of nuclear-encoded mitochondrial genes in epithelial cell clusters

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Commonly used drugs include metoclopramide (Reglan), ondansetron (Zofran) and Cerenia