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Growth hormone secretagogues are performance-adjacent by design

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simultaneous mutagenesis of two or more contiguous amino acid positions is done using an oligonucleotide that contains contiguous N,N,G/T triplets, i.e

Captive animals were maintained under standard husbandry conditions (e.g., ad libitum food, absence of predators and competitors), which relax the constraints imposed by tradeoffs among competing functions

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