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The need of redox-sensitive fluorescent tags (e.g., roGFP2) coupled with microfluidic cell sorting will allow the profiling of OS heterogeneity within endothelial, vascular smooth muscle, and immune cell populations (Schwarzlnder et al., 2016)

131 Intriguingly, pathways through the junctional complex or across the cells actively that participate in transport of ions, nutrients and other molecules could also be potential routes for drug delivery, which is discussed in detail in Section 3.1

19 HA creates volume and turgor of the skin through water attraction into the extracellular matrix, binding up to 1000 times its volume in water, to promote tissue hydration