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With topical corticosteroids as the primary treatment, ACD is currently a pathology without a permanent cure

Chronic inflammation Inflammation is a fundamental mechanism that maintains homeostasis in response to tissue damage (Racanelli et al., 2018

Helps convert melanin from the darker eumelanin to the lighter pheomelanin, reducing skin pigmentation

Adipocyte size analysis was performed using the Keyence BZ-X Analyzer software based on brightfield images of H&E-stained paraffin sections

Clin Infect Dis 51(12):14291434 de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LAB, van der Meer JWM, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, van de Veerdonk FL (2014) IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans