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Notably, such effects are mediated by the phosphorylation-dependent activation of the calcium/cAMP response element binding protein (CREB) that binds to calcium/cAMP regulatory elements (CREs) on DNA

1, 25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D

Among the conventional routes of drug delivery to the retina, including the topical, intravitreal, periocular, suprachoroidal, and systemic routes, intravitreal injection (IVI) is the preferred one [6]

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Given that free cuprous ions catalyse hydroxyl radical formation via the Fenton and HarberWeiss reactions [13, 17], hydrogen peroxide levels were measured in copper-treated cells