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Secondly, BAs synergistically enhance GLP-1 synthesis through TGR5/FXR co-activation on L-cells (Lee et al., 2012)

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Coherently, 96 h of incubation with CM derived from low-expressing PHGDH cells produced a more prominent reduction in muscle fiber width than following the incubation with high-expressing PHGDH cells-derived CM (Fig