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When it comes to the gut, apigenin affects Enterococcus caccae cell wall/membrane synthesis and increases the incidence of protein misfolding Bacteroides galacturonicus growth was also inhibited by apigenin[and] apigenin promoted overall growth and diversity, lowered Firmicutes to Bacteroidetes ratio, and promoted production of short chain fatty acids, including butyrate, which is associated with health (Wang et al., 2017)

When both molecules are present in healthy levels, metabolic processes operate with greater stability

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Week 1 experiment: Administer DSIP 3 hours before intended sleep Track time to fall asleep, sleep quality, morning alertness Note any grogginess or sleep disturbance Week 2 experiment: Administer DSIP 1.5 hours before intended sleep Track the same variables Compare results to week 1 Week 3 experiment: Administer DSIP 30-45 minutes before intended sleep Track and compare Identify which timing produced the best results Some users find their optimal timing changes over a cycle