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Accumulation of ROS plays a crucial role in the pathogenesis of cardiomyopathy, leading to myocardial fibrosis, ventricular remodelling and direct damage to cardiomyocytes (74)

c , BN-PAGE immunoblot on isolated WAT mitochondria from Control and Bmal1-KO mice at ZT14 using an antibody mix against OXPHOS complex subunits (n = 4)