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FOXO4-DRI is supplied as a lyophilised solid and is intended exclusively for in-vitro research and laboratory investigation by qualified professionals

No standardized human dosing exists, and individual responses vary considerably

For weight management, some patients may use the medication until achieving their goal weight and then attempt to maintain weight loss through lifestyle modifications alone, while others may require continued treatment to prevent weight regain

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The one human trial that will measure tolerability directly has not started reporting it is only recruiting (planned 2026), studies a topical gel on small standardized wounds , and lists safety as a secondary, not primary, outcome (NCT07437586)