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Cell Metab (2019) 29:335347 e5

Atherosclerosis 220 , 381386 (2012)

Other agents triggering Nrf2 pathway as dimethyl fumarate and tertio butyl hydroquinone exhibited similar effects as SFN (data not shown)

The rate-limiting step in the de novo synthesis of the GSH is catalyzed by gamma-glutamyl-cysteine synthetase (also known as glutamine-cysteine ligase), which is a target gene of Nrf2