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This protein acts as a molecular "don't eat me" signal to the host's macrophages, the immune cells responsible for engulfing and destroying pathogens

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44 In a targeted amino acid profiling study, Socha et al demonstrated significantly lower circulating concentrations of cysteine and glycinethe rate-limiting substrates for GSH synthesisin MCI subjects relative to cognitively normal elderly controls 45 Likewise, studies have shown that identified a distinct serum amino acid signature in AD patients, marked by diminished branched-chain amino acids and perturbed glutamate metabolism, changes that likely reflect systemic redox imbalance