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It shifts melanin production from darker eumelanin toward lighter phaeomelanin

For translational applications, sustained intranasal delivery aligns far closer with canonical, long-term longevity phenotypes Source: Open Access Paper: Middle-aged mice treated with GHK-Cu peptide administered intraperitoneally or intranasally show behavioral rescue but divergent hippocampal aging programs Institution: University of Washington, Seattle, WA Country: USA Journal: bioRxiv (Preprint) Impact Evaluation: The impact score of this journal is 0 (as a preprint server without a formal Clarivate index)

In the present study, we have found nine antioxidant compounds in bael gum (Retronecine, 1-Naphthylamine, Norbelladine, Celereoin, 1-Methoxy-1H-indole-3-carboxaldehyde, Vinyl caffeate, Aegelinol, Serinyl-Hydroxyproline, Annofoline, and 7b-Hydroxy-3-oxo-5b-cholanoic acid), which can be used for different purposes such as food processing, cosmetics, pharmaceuticals, and other uses

These studies have examined its stability in gastric acid and its systemic availability following different routes of administration in controlled laboratory settings

Experimental validation Dose response curves and determination of IC 50 values were assessed for the 12 candidate drugs using 3-fold dilution series (see Supplementary Methods (Supplementary File 1) for more details)