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The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1

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Immunoblots Cells or tissues were lysed in buffer (150 mM NaCl, 10 mM Tris pH 7.6, 0.1% SDS and 5 mM EDTA) containing protease and phosphatase inhibitors (Thermo Fisher Scientific, 78445)

Pickering CR, Zhou JH, Lee JJ, Drummond JA, Peng SA, Saade RE, et al

Luteolin has exerted its anti-inflammatory effect by inhibiting pro-inflammatory mediators such as cyclooxygenase-2 (COX-2), nitric oxide (NO), TNF-, IL-, IL-6, IL-8, IL-31, and IL-33 in several in vitro models of AD [42], PD [43, 44], MS [45], and in vivo models of AD [27, 46]