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We reveal that OsBAK1 interacts with and phosphorylates OsSRF3 to activate PTI responses, whereas UgsL promotes OsSRF3 degradation through the ubiquitin-26S proteasome, thereby inhibiting OsBAK1OsSRF3-mediated immune pathways

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Provided that astrocytes are the main steroidogenic cells in the brain ( In addition, TLR signaling may play a neuroprotective role in EAE and by extension, in MS, although this effect might not be astrocyte-specific

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It regulates mitochondrial activity through modulation of transcription factors and is a crucial cofactor in the -oxidation of fatty acids, which facilitates the cellular energy production process (Sahebnasagh et al., 2022), balancing hypertonicity-induced imbalances between oxygenase and antioxidant enzymes, reducing ROS production, inhibiting lipid peroxidation, preventing oxidative DNA damage, and suppressing the production of heme oxygenase-1 and cyclooxygenase-2