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TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in tissue repair and cell migration

Moroncini G, Svegliati Baroni S, Gabrielli A (2018) Agonistic antibodies in systemic sclerosis

doi: 10.1038/s41375-020-1000-0 27 KimSJLimJQLaurensiaYChoJYoonSELeeJYet al

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That being said, the high doses of the nootropic measured at 0.5 mg/kg/day for intraperitoneal delivery and 2.0 mg/kg/day for oral delivery, and resulted in a performance that was indistinguishable from the control group and significantly better than the animals treated with scopolamine alone [2]